Our lab was founded in 2022, with the goal to understand the neuronal mechanisms involved in memory and cognition and how imbalances in the circuits can lead to pathological conditions. In particular, we study spatial memory, and theta oscillations in behaving rats, and how the distributed populations of neurons across the distributed brain circuits central to memory, are coordinating their dynamics to generate complex cognitive functions in awake rodents.

We are using state-of-the-art methods for measuring and manipulating the neuronal activity at large-scale and high specificity, together with advanced data analysis. This includes using Neuropixels and other high-density silicon probes, applying optogenetics, thermal and other perturbation techniques, dimensionality reduction, and other advanced population-analysis methods.

We are also strong supporters of open science and have developed multiple tools and solutions for the neuroscience community (both software and hardware solutions. We build CellExplorer – a framework for analyzing single cells and are currently developing BrainSTEM – a collaborative electronic lab notebook for FAIR experimental neuroscience. Our hardware development includes 3D printed and machined microdrives and head cap systems and surgical protocols.


Large-scale electrophysiology

We implant Neuropixels probes and other high-density silicon probes to record hundreds of single neurons and population dynamics across multiple brain regions in behaving rodents.

Circuit and behavioral perturbation

We use optogenetic tools and thermal perturbation to manipulate the activity of genetically defined cell types and brain regions in order to dissect their contribution to behaviors and cognitive functions.

Behavioral paradigms

We develop novel behavioral tasks for complex spatial learning to understand the cognitive processes involved.

Data analysis and theory

We apply novel analysis methods for large-scale neural datasets (both single cells, population level and LFP analysis methods). Our experiments are guided by theory and computational models.

Imaging techniques

We use histological methods together with advanced imaging techniques.